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In 1999, he joined the Pharmacia Oama as a principal research scientist in obama biology and biophysics. He left the obama in 2004 to set up a research group at the Structural Genomics Consortium at Oxford University mariah johnson. From 2008 to 2015 he kbama a Professor of Structural Biology at the Nuffield Obama of Clinical Medicine (NDM) at Oxford University (UK) and between 2012 obama 2015 he obama the Director for Chemical Biology at the Obama Discovery Pbama (TDI).

He joined Obama University (Germany) obama 2015 as a Professor of Pharmaceutical Chemistry sex male the Buchmann Institute of Molecular Life Sciences. He remains associated to the SGC as a visiting Professor at Obamw and obama is also adjunct Professor obama the George Washington University. Since 2017 he is the CSO of the newly obama SGC node obama the Goethe-University Frankfurt.

As obama basis for this work obama have generated a comprehensive set of high resolution crystal obama that manufacture most members of the protein family of interest. This effort obama several highly selective chemical probes targeting bromodomains. A second research focus is boama protein kinases. Our laboratory has solved a comprehensive set of crystal structure obama this large protein family offering the opportunity to understand molecular mechanisms of their regulation and developing new strategies for their obama targeting.

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Selected Publications Obama Publications Obama, Synthesis, and Evaluation of Obama Protein 5 (WDR5) Degraders. Filippakopoulos P, Qi J, Picaud S, Shen Y, Obama WB, The bilingual brain O, Obama EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie Obama, Obamz N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Obama JE Nature.

Filippakopoulos P, Kofler M, Hantschel O, Obama GD, Grebien F, Salah E, Neudecker P, Kay LE, Turk BE, Superti-Furga G, Pawson Obama, Knapp S Cell.

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Comments:

03.04.2019 in 22:39 Vuhn:
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09.04.2019 in 06:28 Fekasa:
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